In 1995, researchers identified the glyoxylate cycle in nematodes.
2.
Examples of amphibolic pathways are the citric acid cycle and the glyoxylate cycle.
3.
The glyoxylate cycle produces four-carbon dicarboxylic acids that can enter gluconeogenesis.
4.
The glyoxylate cycle may serve an entirely different purpose in some species of pathogenic fungi.
5.
More research is needed to identify inhibitors that selectively target enzymes in the glyoxylate cycle.
6.
The net result of the glyoxylate cycle is therefore the production of glucose from fatty acids.
7.
In the glyoxylate cycle of plants and some prokaryotes, isocitrate lyase produces glyoxylate and succinate from isocitrate.
8.
The glyoxylate cycle bypasses the steps in the citric acid cycle where carbon is lost in the form of CO 2.
9.
The levels of the main enzymes of the glyoxylate cycle, ICL and MS, are greatly increased upon contact with a human host.
10.
During his PhD studies Smith collaborated with John Bedbrook at the Plant Breeding Institute to clone the first beta-oxidation and the glyoxylate cycle.